Porous Silicon Biosensors
نویسنده
چکیده
منابع مشابه
The importance of surface chemistry in mesoporous materials: lessons from porous silicon biosensors.
The ease of fabricating high quality photonic crystals from porous silicon and its biocompatibility have inspired the conception of various biosensing schemes using this material. However, the instability of porous silicon has significantly slowed progress in this area. Here we discuss the potential of different porous silicon photonic crystals for biosensing in the context of its surface chemi...
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Photonic bandgap (PBG) structures have remarkable optical properties that can be exploited for biosensing applications. We describe the fabrication of 1-D PBG biosensors using porous silicon. The optical properties of porous silicon PBGs are sensitive to small changes of refractive index in the porous layers, which makes them a good sensing platform capable of detecting binding of the target mo...
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A photochemical functionalization process which passivates the porous silicon surface of optical biosensors has been optimized as a function of the thickness and the porosity of the devices. The surface modification has been characterized by contact angle measurements. Fluorescence measurements have been used to investigate the stability of the DNA single strands bound to the nanostructured mat...
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Porous silicon waveguide biosensors that utilize grating couplers etched directly into porous silicon are demonstrated for improved molecular detection capabilities. Molecules are infiltrated through the grating couplers into the waveguide where they can interact with a guided waveguide mode. Hybridization of nucleic acids inside the waveguide is shown to significantly perturb the wave vector o...
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